Our immune system is essential to our survival. It is complex and not completely understood, but we are witnessing exciting advances in immunotherapy, and more are on the way. For those who are aware of these advances, this study group will allow you to gain a systematic understanding and appreciation of the foundational concepts and principles underlying how the components of the immune system fit together, protect us from disease, and work the way they do. We’ll study the numerous cell types that circulate throughout the body or reside in particular tissues, and how each are unique in recognizing problems, communicating with each other, and performing their functions. We will gain a better understanding of how this knowledge is leading to a revolution in medical treatment. Our text, How the Immune System Works, sixth edition by Lauren Sompayrac (Wiley, 2019), is the primary source for our studies. It cuts through the jargon and details using lively prose and engaging analogies to reveal the biological science which is the essence of the human immune system. We welcome all members regardless of prior knowledge who are prepared to actively participate in a unique, intellectually challenging peer learning experience. Canvas used extensively.